The baby's parents would undoubtedly be stressed out when the baby is crying and screaming from colic. It is a parent's natural instinct to try to make the baby comfortable and the parent would be worried and stressed when the parent's effort fail to stop the crying. This is made worse and more challenging if the parent is already tired and frustrated; and can introduce significant tension in the parent-parent and parent-child relationship. As such, parents should seek help and advice to cope with the problems caused by colic.

If the parent is too tired to take care of a crying child, it is best to get someone else to take over watching for the baby. If there is no one available to take over, the parent should put the baby down in a safe place that does not require immediate supervision and walk away for a while to some nearby place to get some relief from the stress. Crying by itself will not harm the baby and walking away for a while would be overall more positive than to have a frustrated parent trying to comfort an irritable baby. Also, if the parent is already frustrated, the baby can pick up the emotion from the parent and make matters worse. On the other hand, parents should not worry about spoiling the baby. It is ok to respond every time the baby cries. If the baby has colic, it is probably more important to soothe the baby and reduce any discomfort rather than worry about the baby being spoilt.

Since it is important for the parent to get some time off for themselves, the parent should arrange for someone to take over periodically. The best people to do this is the partner, a close friend or a relative. Taking short breaks of an hour or two will do the parent and the parent-child relationship a world of good. The parent should make sure that this time off is used to de-stress and relax instead of doing other things like house chores. Some good suggestions include taking a quick nap, reading a book or simply sitting alone in the garden.

The baby's parents should also get emotional support from friends who have been through the experience of taking care of a baby suffering from colic. If possible, the parents should join an online support forum or a local support group where they can share and talk about the problem. Besides getting new tips that may help, the parents can also get encouragement knowing that there are other real people who are also facing the same problems.